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Perimenopause starts when the intervals between periods begin to lengthen, and it ends with menopause itself (the complete cessation of menstruation).

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Primary dysmenorrhea is caused by prostaglandins, hormone-like substances that are produced in the uterus and cause the uterine muscle to contract.

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If she admits having noticed a personality change and the change corresponds to the type of troublesome emotional patterns commonly associated with PMS, then I can hypothesize that her pregnancy spurred the development of a serious bacterial infection that caused her to develop PMS and perhaps, secondary infertility as well.

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The effects of magnesium are not as well established as with calcium, but some evidence suggests that it may be helpful in reducing fluid retention in women with mild PMS.

Breier et al reported a higher number of panic attacks in 14 of 43 (33%) women with panic disorder, and Hsiao et al also reported premenstrual exacerbation of panic attack frequency in 30% of patients studied.

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Estrogen and progesterone, found in oral contraceptive formulations and the medroxy-progesterone contraceptive injection (Depo-Provera), may cause lactation.

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Until relatively recently (and it is still be true in some cases), physicians in some states actually lost their license to practice medicine because they were giving narcotics to patients with non-terminal illnesses.

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Assuming I don't notice any specific symptoms and I can't account for possible bacterial infection by reviewing my family or sexual history, when should I consider being checked for bacterial infection in my genital tract?

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Physical examination, cross-sectional imaging studies of the abdomen, and relevant laboratory tests will often confirm the diagnosis during the acute episode.

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